Rx
Tablet/CapsuleCapsule

Koselugo 10mg Capsule

by AstraZeneca

bottle of 60 capsules
MRP ₹408796.886813.28/Units
*MRP inclusive of all taxes

In Treatment of Neurofibromatosis type 1 (NF1) Koselugo 10mg Capsule is used to treat children aged 2 years and above with neurofibromatosis type 1 (NF1), particularly those with symptomatic, inoperable tumors. Koselugo 10mg Capsule helps slow tumor growth and

Generic Name
Selumetinib (10mg)
Form
Capsule
Manufacturer
Pack Size
bottle of 60 capsules
Prescription
Prescription Required
Common Side Effects
HeadacheFatigueNauseaVomiting+9 more
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About this Medicine

Koselugo 10mg Capsule is used to treat children aged 2 years and older with neurofibromatosis type 1 (NF1), a genetic condition that causes the growth of tumors on nerve tissues. It works by targeting a protein involved in tumor growth. It helps slow the growth of tumors and provides relief from the symptoms. Koselugo 10mg Capsule can be taken with or without food. It should be taken exactly as prescribed by the doctor. It should be taken regularly and at the same time each day for the best outcomes. To maximize the benefits, follow all instructions carefully and get regular check-ups to monitor the progress of the treatment.Common side effects of Koselugo 10mg Capsule include nausea, vomiting, diarrhea, abdominal pain, fatigue, musculoskeletal pain, fever, and rashes. For mild side effects, the doctor may recommend staying hydrated or resting when feeling fatigued. However, for severe or persistent symptoms, such as extreme stomach pain, yellowing of the skin or eyes, or difficulty breathing, seek immediate medical attention.While on treatment with Koselugo 10mg Capsule, grapefruit or grapefruit juice should be avoided, as it can interfere with how the medication works. This medicine should be used cautiously in patients who have a history of liver or heart problems. Additionally, activities that may increase the risk of infections or injury should be avoided, as the medicine can sometimes weaken the immune system or make the patient more prone to bruising.

How it Works

Koselugo 10mg Capsule works by blocking a protein called MEK, which is part of a system in the body that controls cell growth. In neurofibromatosis type 1 (NF1), this system can become too active because of a genetic change, causing tumors called plexiform neurofibromas to grow. By turning off MEK, Koselugo 10mg Capsule helps slow down or shrink these tumors, reducing symptoms like pain or difficulty moving, and improving the patient’s daily life.

Key Facts

Chemical Class :: Benzimidazoles|Habit Forming :: No|Action Class :: MEK inhibitor

Safety Overview

Alcohol
CONSULT YOUR DOCTOR
Pregnancy
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Lactation
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Driving
UNSAFE
Kidney
SAFE IF PRESCRIBED
Liver
CAUTION

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MRP
408796.88
Koselugo 10mg Capsule — Uses, Side Effects & Price | FulMeds